The miR-144/451 locus is required for erythroid homeostasis
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چکیده
منابع مشابه
The miR-144/451 locus is required for erythroid homeostasis
The process of erythropoiesis must be efficient and robust to supply the organism with red bloods cells both under condition of homeostasis and stress. The microRNA (miRNA) pathway was recently shown to regulate erythroid development. Here, we show that expression of the locus encoding miR-144 and miR-451 is strictly dependent on Argonaute 2 and is required for erythroid homeostasis. Mice defic...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2010
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.20100458